Publikacje

» 2016

  1. K.Kuder, D.Łażewska, G.Latacz, J.Schwed, T.Karcz, H.Stark, J.Karolak-Wojciechowska, K.Kieć-Kononowicz: Chlorophenoxy aminoalkyl derivatives as histamine H3R ligands and antiseizure agents; Bioorg. Med. Chem. 24, 53-72, 2016.
  2. K.Kucwaj-Brysz, D.Warszycki, S.Podlewska, J.Witek, K.Witek, A.Gonzalez Izquierdo, G.Satała, M.Loza, A.Lubelska, G.Latacz, A.Bojarski, M.Castro, K.Kieć-Kononowicz, J.Handzlik: Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation; Eur. J. Med. Chem. 13, 258-269, 2016.
  3. J.Bohnert, S.Schuster, W.Kern, T.Karcz, A.Olejarz, A.Kaczor, J.Handzlik, K.Kieć-Kononowicz: Novel piperazine arylideneimidazolones inhibit the AcrAB-TolC pump in Escherichia coli and simultaneously act as fluorescent membrane probes in a combined real-time influx and efflux assay; Antimicrob. Agents Chemother. 60(4), 1974-1983, 2016.
  4. G.Latacz, P.Kechagioglou, R.Papi, D.Łażewska, M.Więcek, K.Kamińska, P.Wencel, T.Karcz, J.Schwed, H.Stark, D.A.Kyriakidis, K.Kieć-Kononowicz: The synthesis of 1,3,5-triazine derivatives and JNJ7777120 analogues with histamine H4 receptor affinity and their interaction with PTEN promoter; Chem. Biol. Drug Des. 88(2), 254-263, 2016.
  5. E.Otrębska-Machaj, J.Chevalier, J.Handzlik, E.Szymańska, J.Schabikowski, G.Boyer, J.-M.Bolla, K.Kieć-Kononowicz, J.-M.Pages, S.Alibert: Efflux pump blockers in Gram-negative bacteria; The new generation of hydantoin based-modulators to improve antibiotic activity; Front. Microbiol. 7, 1-8, 2016.
  6. M.Dudek, K.Kuder, M.Kołaczkowski, A.Olczyk, E.Żmudzka, A.Rak, M.Bednarski, K.Pytka, J.Sapa, K.Kieć-Kononowicz: H3 histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice; Metab. Brain Dis. 31(5):1023-1029, 2016.
  7. M.Grosicki, T.Wójcik, S.Chłopicki, K.Kieć-Kononowicz: In vitro study of histamine and histamine receptor ligands influence on the adhesion of purified human eosinophils to endothelium; Eur. J. Pharmacol. 777, 49-59, 2016.
  8. D.Łażewska, J.Jończyk, M.Bajda, N.Szałaj, A.Więckowska, D.Panek, C.Moore, K.Kuder, B.Malawska, K.Kieć-Kononowicz: Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands; Bioorg. Med. Chem. Lett. 26(16), 4140-4145, 2016.
  9. C.Flegel, F.Vogel, A.Hofreuter, S.Wójcik, C.Schoeder, K.Kieć-Kononowicz, N.Brockmeyer, C.Müller, C.Becker, J.Altmüller, H.Hatt, G.Gisselmann: Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18; Sci. Rep. 6, 32255, 2016 (doi:10.1038/srep32255).
  10. B.Sadek, A.Saad, D.Subramanian, M.Shafiullah, D.Łażewska, K.Kieć-Kononowicz: Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats; Neuropharmacology 106, 46-55, 2016.
  11. D.Łażewska, E.Dominguez-Álvarez, K.Kamińska, K.Kuder, K.Kieć-Kononowicz: Monocyclic and fused azines and azoles as histamine H4 receptor ligands; Curr. Med. Chem. 23, 1870-1925, 2016.
  12. A.Dziubina, K.Szmyd, M.Zygmunt, J.Sapa, M.Dudek, B.Filipek, A.Drabczyńska, M.Załuski, K.Pytka, K.Kieć-Kononowicz: Evaluation of antidepressant-like and anxiolytic activity of purinedione-derivatives with affinity for adenosine A2A receptors in mice; Pharmacol. Rep. 68, 1285-1292, 2016.
  13. E.Szymańska, A.Drabczyńska, T.Karcz, C.Müller, M.Köse, J.Karolak-Wojciechowska, A.Fruziński, J.Schabikowski, A.Doroz-Płonka, J.Handzlik, K.Kieć-Kononowicz: Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors; Bioorg. Med. Chem. 24, 4347-4362, 2016.
  14. S.Mogilski, M.Kubacka, D.Łażewska, M.Więcek, M.Głuch-Lutwin, M.Tyszka-Czochara, K.Bukowska-Strakova, B.Filipek, K.Kieć-Kononowicz: Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide; Inflamm. Res. 2016 doi 10.1007/s00011-016-0997-z.
  15.  B.Sadek, A.Saad, G.Latacz, K.Kuder, A.Olejarz, T.Karcz, H.Stark, K.Kieć-Kononowicz: Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats; Drug Des. Devel. Ther. 2016.
  16. R.Wolińska, A.Leśniak, M.Żochowska, M.Sacharczuk, K.Kieć-Kononowicz, M.Bujalska-Zadrożny: Antinociceptive effect of co-administered NMDA and histamine H4 receptor antagonists in a rat model of acute pain; Pharmacol. Rep. dx.doi.org/doi:10.1016/j.pharep.2016.10.018.
  17. E.C.Estevam, S. Griffin, M.J.Nasim, P.Denezkin, R. Schneider, R. Lilischkis, E. Dominguez-Alvarez, K.Witek, G.Latacz, C.Keck, K.-H.Schäfer, K.Kieć-Kononowicz, J.Handzlik, C.Jacob: Natural selenium particles from Staphylococcus carnosus: Hazards or particles with particular promise?; J. Hazard. Mater. dx.doi.org/10.1016/j.jhazmat.2016.02.001.
  18. A.Smarandache, V.Nastasa, M.Boni, A.Staicu, J.Handzlik, K.Kieć-Kononowicz, L.Amaral, M.-L.Pascu: Laser beam resonant interaction of new hydantoin derivatives droplets for possible biomedical applications, Colloids Surf. A: Physicochemical and Engineering Aspects, 505, 37-46, 2016
  19. E.Domínguez-Álvarez, M.Gajdács , G.Spengler , J.A.Palop, M.A.Marć, K.Kieć-Kononowicz, L.Amaral, J.Molnár, C.Jacob, J.Handzlik, C.Sanmartín, Identification of selenocompounds with promising properties to reverse cancer multidrug resistance, Bioorg. Med. Chem. Lett. 26, 2821-2824, 2016
  20. E.Żesławska, A.Kincses, G.Spengler, W.Nitek, K.Wyrzuc, K.Kieć-Kononowicz, J.Handzlik, The 5-aromatic hydantoin-3-acetate derivatives as inhibitors of the tumour multidrug resistance efflux pump P-glycoprotein (ABCB1): Synthesis, crystallographic and biological studies. Bioorg. Med. Chem. 24, 2815–2822, 2016
  21.  A.Smarandache, A.Pascu, I.R.Andrei, J.Handzlik, K.Kieć-Kononowicz, A.Staicu, M.-L.Pascu: Study of the optical properties of 2-thiohydantoin derivatives. Rom. Rep. Phys. 68, 673-683, 2016
  22. K.Śladowska, J.Handzlik, K.Kieć-Kononowicz, L.Mazur: In vitro cytotoxic activity evaluation of phenytoin derivatives against human leukemia cells. In. J. Exper. Biol. 54, 553-559, 2016
  23. S.Griffin, N.K.Tittikpina, A.Al-Marby, R.Alkhayer, P.Denezhkin, K.Witek, K.A.Gbogbo, K.Batawila, R.E.Duval, M.J.Nasim, N.A.Awadh-Ali, G.Kirsch, P.Chaimbault, K.H.Schäfer, C.M.Keck, J.Handzlik, C.Jacob: Turning Waste into Value: Nanosized Natural Plant Materials of Solanum incanum L. and Pterocarpus erinaceus Poir with Promising Antimicrobial Activities.Pharmaceutics. 8, 11, 2016

» 2015

  1. M.Zygmunt, K.Gołembiewska, A.Drabczyńska, K.Kieć-Kononowicz, J.Sapa: Anti-inflammatory, antioxidant, and antiparkinsonian effects of adenosine A2A receptor antagonists; Pharm. Biochem. Behav. 132, 71-78, 2015.
  2. K.Kamiński, A.Rapacz, J.J.Łuszczki, G.Latacz, J.Obniska, K.Kieć-Kononowicz, B.Filipek: Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butan-amide; Bioorg. Med. Chem. 23(10):2548-2561,2015.
  3. M.Szafarz, A.Kryczyk, D.Łażewska,  K.Kieć-Kononowicz, E.Wyska: Pharmacokinetics and tissue distribution of the new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy)propyl]piperidine in rats; Xenobiotica, 45(10):912-920 2015.
  4. M.Grosicki, K.Kieć-Kononowicz: Human eosinophilis – potential pharmacological model applied in human histamine H4 receptor research; Eur. J. Pharmacol. 22, 2037-2099, 2015.
  5. A.Matys, S.Podlewska, K.Witek, J.Witek, A.J.Bojarski, J.Schabikowski, E.Otrębska-Machaj, G.Latacz, E.Szymańska, K.Kieć-Kononowicz, J.Molnar, L.Amaral, J.Handzlik: Imidazolidine-4-one derivatives in the search for novel chemosensitizers of Staphylococcus aureus MRSA: Synthesis, biological evaluation and molecular modeling studies; Eur. J. Med. Chem., 101, 313-325, 2015.
  6. M.Zygmunt, J.Sapa, A.Drabczyńska, T.Karcz, C.E.Műller, M.Kősse, G.Latacz, J.Schabikowski, M.Bednarski, K.Kieć-Kononowicz: Synthesis and analgesic activity of annelated xanthine derivatives in experimental models in rodents; Arch. Pharm. 348, 704-714, 2015.
  7. K.Kamiński, M.Zagaja, J.Łuszczki, A.Rapacz, M.Andres-Mach, G.Latacz, K.Kieć-Kononowicz: Design, synthesis and anticonvulsant activity of new hybrid compounds derived from 2-(2,5-dioxopyrrolidin-1-yl)propanamides and 2-(2,5-dioxopyrrolidin-1-yl)butanamides; J. Med. Chem. , 58, 5274-5286, 2015.
  8. K.Kamińska, J.Ziemba, J.Ner, J.Schwed, D.Łażewska, M.Więcek, T.Karcz, A.Olejarz, G.Latacz, K.Kuder, T.Kottke, M.Zygmunt, J.Sapa, J.Karolak-Wojciechowska, H.Stark, K.Kieć-Kononowicz: (2-Arylethenyl)-1,3,5-triazin-2-amines as novel histamine H4 receptor ligands; Eur. J. Med. Chem., 103, 238-251, 2015.
  9. E.C.Estevam, K.Witek, L.Faulstich, M.J.Nasim, G.Latacz, E.Domínguez-Álvarez, K.Kieć-Kononowicz, M.Demasi, J.Handzlik, C.Jacob: Aspects of a Distinct Cytotoxicity of Selenium Salts and Organic Selenides in Living Cells with Possible Implications for Drug Design; Molecules, 31; 20(8):13894-912, 2015.
  10. G.Latacz, K.Kieć-Kononowicz: The stereoselectivity and hydrolysis efficiency of recombinant d-hydantoinase from Vigna angularis against 5-benzylhydantoin derivatives with halogen and methyl substituents; Appl. Biochem. Biotechnol. 175, 2, 698-704, 2015.
  11. A.Bahi, B.Sadek, S.M.Nurulain, D.Łażewska, K.Kieć-Kononowicz: The novel non-imidazole histamine H3 receptor antagonist DL77 reduces voluntary alcohol intake and ethanol-induced conditioned place preference in mice; Physiol. Behav. 151, 189-197, 2015.
  12. A.Smarandache, V.Nastasa, M.Boni, A.Staicu, J.Handzlik, K.Kieć-Kononowicz, L.Amaral, M.-L. Pascu: Laser beam resonant interaction of new hydantoin derivatives droplets for possible biomedical applications; Colloids Surf. A: Physicochem. Eng. Aspects, dx.doi.org/10.1016/j.colsurfa.2015.12.002.

» 2014

  1. A.Bąk, M.Daszykowski, Z.Kamiński, K.Kieć-Kononowicz, K.Kuder, J.Fraczyk, B.Kolesińska, P.Ciosek, J.Polański: Probing an artificial polypeptide receptor library using a series of novel histamine H3 receptor ligands; Comb. Chem. High Throughput Screen., 17, 141-156, 2014.
  2. J.Handzlik, A.Bojarski, G.Satała, M.Kubacka, B.Sadek, A.Ashoor, A.Siwek, M.Więcek, K.Kucwaj, B.Filipek, K.Kieć-Kononowicz: SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT7 receptor ligands among phenylpiperazine hydantoin derivatives; Eur.J.Med. Chem., 78, 324-339, 2014.
  3. M.Grosicki, G.Latacz, A.Szopa, A.Cukier, K.Kieć-Kononowicz: The study of cellular cytotoxicity of argireline – an anti-aging peptide; Acta  Biochim.Pol. 61 (1), 29-32, 2014.
  4. V.Rempel, K.Atzler, A.Behrenswerth, T.Karcz, C.Schoeder, S.Hinz, M.Kaleta, D.Thimm, K.Kieć-Kononowicz, C.E.Müller: Bicyclic imidazole-4-one derivatives: new class of antagonists for the orphan G protein-coupled receptors GPR18 and GPR55, Med. Chem. Commun. 5, 632-649, 2014.
  5. B.Sadek, K.Kuder, D.Subramanian, M.Shafiullah, H.Stark, D.Łażewska, A.Adem, K.Kieć-Kononowicz: Anticonvulsive effect of nonimidazole histamine H3 receptor antagonists; Behav. Pharm. 25, 3, 245-252, 2014.
  6. G.Latacz, K.Kieć-Kononowicz: Biotransformation of new racemic (R,S)-5-benzylhydantoin derivatives by D-hydantoinases from adzuki bean; Biocatal. Biotransf. 32, 2, 117-124, 2014.
  7. E.Schlicker, A.Pędzińska-Betiuk, H.Kozłowska, N.Szkaradek, D.Żelaszczyk, M.Baranowska-Kuczko, K.Kieć-Kononowicz, H.Marona, B.Malinowska: MH-3: evidence for non-competitive antagonism towards the low-affinity site of α1-adrenoceptors; Naunyn-Schmied. Arch. Pharmacol. 387, 8, 743-752, 2014.
  8.  D.Łażewska, M.Więcek, J.Ner, K.Kamińska, T.Kottke, S.Schwed, M.Zygmunt, T.Karcz, A.Olejarz, K.Kuder, G.Latacz, M.Grosicki, J.Sapa, J.Karolak-Wojciechowska, H.Stark, K.Kieć-Kononowicz: Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands; Eur. J. Med. Chem. 83, 534-546, 2014.
  9. K.Kuder, M. Stachnik, W.Schunack, E.Szymańska, K.Kieć-Kononowicz: Discovery of novel lead in the group of N-substituted piperazine ether derivatives with potential histamine H3 receptor activity; Med. Chem., 10, 588-599, 2014.
  10. K.Kuder, K.Kieć-Kononowicz Fluorescent GPCR ligands as new tools in pharmacology-update, years 2008-early 2014; Cur. Med. Chem. 21, 3962-3975, 2014

 

» 2013

  1. E.Szymanska, J.Mazurkiewicz, K.Kieć-Kononowicz: Methods for the synthesis of the xanthine derived polycyclic fused systems Heterocycl. Commun. 19, 297-373, 2013
  2. J.Handzlik, E.Szymańska, S.Alibert, J.Chevalier, E.Otrębska, E.Pękala, J.-M.Pages, K.Kieć-Kononowicz: Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin; Bioorg. Med. Chem., 21, 135-145, 2013
  3. B.Sadek, A. Adem, S. Shehab, M. Więcek, D. Subramanian, M. Shafiullah, K. Kieć-Kononowicz: Anticonvulsant properties of histamine H3 receptors ligands belonging to N- substituted carbamates of imidazopropanol Bioorg. Med. Chem. Lett. 23, 17, 4886-4891, 2013
  4. P.Koch, R.Akkari, A.Brunschweiger, T.Borrmann, M.Schlenk, P.Küppers, M.Köse, H.Radjainia, J.Hockenmeyer, A.Drabczyńska, K.Kieć-Kononowicz, C.E.Müller: 1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases Bioorg. Med. Chem 21, 7435-7452, 2013
  5. A.Drabczyńska, T.Karcz, E.Szymańska, M.Köse, C.E.Müller, M.Paskaleva, J.Karolak-Wojciechowska, J.Handzlik, O.Yuzlenko, K.Kieć-Kononowicz: Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones. Purinergic Signal. 9, 395-414. 2013
  6. D.Łażewska, K.Kieć-Kononowicz: New developments around H3 receptor antagonists/inverse agonists: a patent review (2010 – present). Expert Opin. Ther. Patents 24, 1-23, 2013
  7. A. Szymańska, G.Latacz, K.Kieć-Kononowicz: Wykorzystanie tkanek autologicznych w medycynie estetycznej, dermatochirurgii i kosmetologii. Pol. J. Cosmetol. 16(2), 127-132, 2013
  8. J.Handzlik, A.Matys, K.Kieć-Kononowicz: Recent advances in multi-drug resistance (MDR) Efflux pump inhibitors of Gram-positive bacteria S. aureus. Antibiotics, 2, 28-45, 2013
  9. T. Karcz, K.Kieć-Kononowicz: Development of novel cellular model for affinity studies of histamine H4 receptor ligands. Acta Biochim Pol. 60 (4) 823-827, 2013

» 2012

  1. D.Łażewska, K. Kieć-Kononowicz: Azines as histamine H4 receptor antagonists; Frontiers in Bioscience S4, 967-987, 2012,
  2. J.Handzlik, G.Spengler, B.Mastek, A.Dela, J.Molnar, L.Amaral, K.Kieć-Kononowicz: 5-Arylidene (thio)hydantoin derivatives as modulators of cancer efflux pump; Acta Polon. Pharm.-Drug Res. 69, 1, 149-153, 2012,
  3. R.Venskutonyte, K.Frydenvang, E.A.Valades, E.Szymańska, T.N.Johansen, J.S.Kastrup, D.S.Pickering: Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors; Chem. Med. Chem. 7, 1-7, 2012,
  4. M.Bajda, K.Kuder, D.Łażewska, K.Kieć-Kononowicz, A.Więckowska, M.Ignasik, N.Guzior, J.Jończyk, B.Malawska: Dual-acting Diether derivatives of piperidine and homopiperidine with histamine H3 receptor antagonistic and anticholinesterase activity; Arch. Pharm. Chem. Life Sci. 348, 8, 591-597, 2012,
  5. A.Dymek, A.Armada, J.Handzlik, M.Viveiros, G.Spengler, J.Molinar, K.Kieć-Kononowicz, L.Amaral: The activity of 16 new hydantoin compounds on the intrinsic and over-expressed efflux pump system of Staphyloccocus aureus; In vivo, 26, 223-229, 2012
  6. A.Martins, A.Dymek, J.Handzlik, G.Splenger, A.Armada, J.Molnar, K.Kieć-Kononowicz: Activity of fourtheen New hydantoin compounds on the human ABCB1 efflux pump; In Vivo, 26(2), 293-7, 2012,
  7. J.Handzlik, E.Szymańska, R.Wójcik, A.Dela, M.Jastrzębska-Więsek, J.Karolak-Wojciechowska, A.Fruziński, A.Siwek, B.Filipek, K.Kieć-Kononowicz: Synthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α1-adrenoceptor antagonistic properties; Bioorg. Med. Chem., 20(14), 4245-57, 2012, JCR
  8. J.Handzlik, M.Bajda, M.Zygmunt, D.Maciąg, M.Dybała, M.Bednarski, B.Filipek, B.Malawska, K.Kieć-Kononowicz: Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α1-adrenoceptor affinities; Bioorg. Med. Chem. 20 2290-2303, 2012
  9. B.Gzyl-Malcher, J.Handzlik, E.Klekowska: Interaction of prazosin with model membranes – A Langmuir monolayer study; Bioelechem. 87, 96-103, 2012
  10. L.Amaral, G.Spengler, A.Martins, A.Armada, J.Handzlik, K.Kieć-Kononowicz, J.Molnar: Inhibitors of bacterial efflux pumps that also inhibit efflux pumps of cancer cells; Anticanc. Res. 32, 2947-2957, 2012

» 2011

  1. J.Handzlik, E.Szymańska, K.Nędza, M.Kubacka,A.Siwek, Sz.Mogilski, J.Handzlik, B.Filipek, K.Kieć-Kononowicz: Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin; Bioorg. Med. Chem.; 19, 1349-1360, 2011
  2. A.Drabczyńska, M.Zygmunt, J.Sapa, B.Filipek, C.E.Müller, K.Kieć-Kononowicz: Antiparkinsonian effects of novel adenosine A2A receptor antagonists; Arch. Pharm. Chem. Life Scien., 1, 20-27, 2011
  3. M.Szafarz, J.Szymura-Oleksiak, D.Łażewska, K.Kieć-Kononowicz: LC-MS-MS method for the analysis of new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy)propylpiperidine in rat serum – application to pharmacokinetic studies; Chromatographia, 73, 913-919, 2011
  4. E.Pękala: Kolory biotechnologii; Przemysł farmaceutyczny, 2, 29-31, 2011
  5. M.Więcek, T.Kottke, X.Ligneau, W.Schunack, R.Seifert, H.Stark, J.Handzlik, K.Kieć-Kononowicz: N-alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands; Bioorg. Med. Chem. 19, 2850-2858, 2011
  6. A.Drabczyńska, O.Yuzlenko, M.Kőse, M.Paskaleva, A.Schiedel, J.Karolak-Wojciechowska, J.Handzlik, T.Karcz, K.Kuder, C.E.Müller, K.Kieć-Kononowicz: Synthesis and biological activity of tricyclic cycloalkylimidazo- pyrimido- and diazepinopurinediones; Eur. J. Med. Chem. 46, 3590-3607, 2011
  7. J.M.Bolla, S.Alibert-Franco, J.Handzlik, J.Chevalier, A.Mahamoud, G.Boyer, K.Kieć-Kononowicz, J.-M.Pagès: Strategies for bypassing the membrane barier in multidrug resistant Gram-negative bacteria; FEBS Let., 585,1682-1690, 2011
  8. L.Machado, G.Spengler, M.Evaristo, J.Handzlik, J.Molnar, M.Viveiros, K.Kieć-Kononowicz, L.Amaral: Biological activity of twenty-three hydantoin derivatives on intrinsic efflux pump system of Salmonella enteric serovar enteritidis NCTC 13349; In vivo 25, 769-772, 2011
  9. G. Spengler, J. Handzlik, I. Ocsovszki, M. Viveiros, K. Kieć-Kononowicz, L. Amaral; J. Molnár, Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adrenocarcinoma cells without inducing apoptosis, Anticancer Res., 31, 3285-3288, 2011
  10. J. Handzlik, E. Szymańska, J. Chevalier, E. Otrębska, K. Kieć-Kononowicz, J.-M. Pagès, S. Alibert; Amine-alkyl derivatives of hydantoin: new tool to combat resistant bacteria, Eur. J. Med. Chem. 46, 5807-5816,  2011
  11. D.Łażewska, J.Karolak-Wojciechowska, B. Kolesińska, Z. Kamiński, K.Kieć-Kononowicz: Convenient way of synthesis and crystal structure of JNJ 7777120 Heterocycl. Commun. 17, 207-210, 2011
  12. A. Stasiak, M. Mussur, M. Unzeta, D. Łażewska, K. Kieć-Kononowicz, W.A. Fogel: The central histamine level in rat model of vascular dementi; J. Phys. and Pharm., 62, 549-558, 2011.

» 2010

  1. J.Karolak-Wojciechowska, E.Szymańska, A.Fruziński, K.Kieć-Kononowicz: Crystallographic studies of (Z) and (E) isomers of 2-amino-5-(2-chlorobenzylidene)-1-methyl-1H-imidazol-4(5H)-one; J. Mol. Str. 966, 14-17, 2010
  2. K.Kuder, T.Kottke, H.Stark, X.Ligneau, J.-C.Camelin, R.Seifert, K.Kieć-Kononowicz: Search for novel, high affinity histamine H3 receptor ligands with fluorescent properties; Infl. Res. Suppl. 2, 59, S247-S248, 2010
  3. T.Karcz, J.Handzlik, D.Łażewska, T.Kottke, R.Seifert, K.Kieć-Kononowicz: Search for histamine H4 receptor ligands in the group of 4-methylpiperazino amide derivatives; Infl. Res. Suppl. 2, S243-S245, 2010
  4. K.Słoczyńska, E.Pękala, A.Wajda, G.Węgrzyn, H.Marona: Evaluation of mutagenic and antimutagenic properties of some bioactive xanthone derivatives using Vibrio harveyi test; Let. Appl. Mircobiol., 50, 252-257, 2010
  5. H.Marona, A.Gunia, E.Pękala: Retinoidy – rola w farmakoterapii w aspekcie komórkowego mechanizmu działania; Farm. Pol. 66, 3, 187-192, 2010
  6. A.Waszkielewicz, N.Szkaradek, E.Pękala, F.Galzarano, H.Marona: The study of the lipophilicity of some aminoalkanol derivatives with anticonvulsant activity; Biomed. Chromat. 24, 1365-1372, 2010
  7. P.Kawczak, Y.V.Heyden, A.Nasal, T.Bączek, A.Drabczyńska, K.Kieć-Kononowicz, R.Kaliszan: Micellar liqiud chromatography for lipophilicity determination of new biologically active 1,3-purinodiones; J.Sep. Sci. 33, 1-12, 2010
  8. I.Subtel’na, D.Atamanyuk, E.Szymańska, K.Kieć-Kononowicz, B.Zimenkovsky, O.Vasylenko, A.Gzella, R.Lesyk: Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity; Bioorg. Med. Chem., 18, 5090-5102, 2010
  9. J.Handzlik, H.H.Pertz, T.Gőrnemann, S.Jähnichen, K.Kieć-Kononowicz: Search for influence of spatial properties on affinity at α1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin; Bioorg. Med. Chem. Lett.; 20, 6152-6156, 2010 D.Łażewska, K.Kieć-Kononowicz: Recent advances in histamine H3 receptor antagonists/inverse agonists; Expert Opin. Ther. Pat., 20, 9, 1147-1169, 2010
  10. G.Spengler, M.Evaristo, J.Handzlik, J.Serly, J.Molnár, M.Viveiros, K.Kieć-Kononowicz, L.Amaral; Biological activity of hydantoin derivatives on P-Glycoprotein (ABCB1) of mouse Lymphoma Cells, Anticancer Res., 30 begin_of_the_skype_highlighting, 4867-4871, 2010
  11. K.Kuder: Alchemia- szarlataneria czy nauka; Moda na farmację; 12, 42, 20-21, 2010